DNA Nanotechnology
Engineered DNA structures and molecular machines
National Institute for Nanotechnology
Edmonton, Canada
Canada's national research facility for nanotechnology research and development
Twist Bioscience
South San Francisco, United States
Twist Bioscience, founded in 2013 in South San Francisco, California, has revolutionized DNA synthesis through its innovative silicon-based nanoscale manufacturing platform. Trading on NASDAQ under ticker TWST, the company employs 500-1000 people and represents a convergence of semiconductor nanotechnology and synthetic biology. Twist's proprietary synthesis platform miniaturizes traditional DNA synthesis chemistry onto silicon chips using semiconductor photolithography and nanofabrication techniques, enabling massively parallel synthesis of oligonucleotides in nanoscale wells. This breakthrough reduces reagent consumption by over 1000-fold compared to conventional column-based synthesis while dramatically increasing throughput and reducing costs. The silicon-based approach allows Twist to synthesize millions of distinct DNA sequences simultaneously on a single chip, with each synthesis occurring in nanoliter or picoliter reaction volumes. The company's core products include custom synthetic genes, gene fragments, oligonucleotide pools, and next-generation sequencing libraries used in drug discovery, agricultural biotechnology, industrial chemicals production, and academic research. Twist has pioneered applications in DNA data storage, leveraging the massive information density of DNA molecules to archive digital data at nanoscale dimensions, with potential to revolutionize long-term data storage. The platform enables rapid design-build-test cycles for synthetic biology applications, accelerating development of therapeutic antibodies, enzymes, and novel biomolecules. Twist's nanotechnology-enabled manufacturing approach addresses the growing demand for synthetic DNA across biotechnology sectors, supporting applications from CRISPR gene editing to vaccine development. The company's success demonstrates how semiconductor nanofabrication techniques can transform biological manufacturing, creating a scalable, high-precision platform for the programmable synthesis of genetic material. As synthetic biology continues to expand, Twist's nanomanufacturing capabilities position it as critical infrastructure for biotechnology innovation, enabling researchers and companies worldwide to access high-quality synthetic DNA quickly and affordably.
Beam Therapeutics
Cambridge, United States
Pioneer in base editing using lipid nanoparticle delivery for precision genetic medicines
Oxford Nanopore Technologies
Oxford, United Kingdom
Pioneer in nanopore DNA/RNA sequencing technology enabling real-time, long-read sequencing
Pacific Biosciences
Menlo Park, United States
Developer of single molecule real-time (SMRT) DNA sequencing technology
Illumina
San Diego, United States
Global leader in DNA sequencing using nanoscale flow cell technology
Pacific Biosciences
Menlo Park, United States
Developer of SMRT sequencing using zero-mode waveguides
Nabsys
Providence, United States
Developer of electronic genome mapping using nanochannels
Quantum Biosystems
Tokyo, Japan
Single-molecule electrical sequencing technology
Prime Medicine
Cambridge, United States
Prime editing therapeutics with LNP delivery
Exicure
Chicago, United States
Spherical nucleic acid therapeutics platform
Egyptian Nanotechnology Society
Cairo, Egypt
Egypt's nanotechnology research network
Kavli Institute of Nanoscience
Delft, Netherlands
TU Delft quantum and nano research
Instituto de Nanotecnologia Mexico
Mexico City, Mexico
UNAM nanotechnology research center
CRISPR Therapeutics
Zug, Switzerland
CRISPR-based gene editing therapeutics for blood disorders and cancer
Editas Medicine
Cambridge, United States
CRISPR-based medicines for genetic diseases including eye disorders
Ginkgo Bioworks
Boston, United States
Cell programming platform for bio-based products and materials
DNA Script
Paris, France
Enzymatic DNA synthesis for on-demand oligo production
Nitto Denko Avecia
Milford, United States
Oligonucleotide and nucleic acid CDMO services
Universidad de Chile Nanoscience
Santiago, Chile
Center for Nanoscience and Nanotechnology
Intellia Therapeutics
Cambridge, United States
CRISPR gene editing company using lipid nanoparticle delivery for in vivo therapeutics
Editas Medicine
Cambridge, United States
Genome editing company using CRISPR with lipid nanoparticle delivery systems
Ionis Pharmaceuticals
Carlsbad, United States
Pioneer in antisense technology and RNA-targeted therapeutics
Exiqon
Vedbaek, Denmark
Locked nucleic acid technology for RNA research and diagnostics
Tempus
Chicago, United States
AI-driven precision medicine with genomic sequencing and diagnostics
Natera
Austin, United States
Cell-free DNA testing for prenatal screening and cancer detection
Invitae
San Francisco, United States
Genetic testing company with comprehensive hereditary cancer panels
Myriad Genetics
Salt Lake City, United States
Molecular diagnostics for hereditary cancer and prenatal screening
23andMe
Sunnyvale, United States
Consumer genetics company with health and ancestry DNA testing
Ancestry
Lehi, United States
Family history and consumer DNA testing using advanced genotyping
Berry Genomics
Beijing, China
Non-invasive prenatal testing and genetic diagnostics in China
MGI Tech
Shenzhen, China
DNA sequencing instruments and reagents using proprietary technology
Universidade de São Paulo Nano
São Paulo, Brazil
Leading Brazilian university with extensive nanotechnology research
Weizmann Institute of Science
Rehovot, Israel
World-class research institute with pioneering nanoscience programs
Hebrew University of Jerusalem Nano
Jerusalem, Israel
Major Israeli university with Center for Nanoscience and Nanotechnology
Seoul National University Nano
Seoul, South Korea
Korea's top university with Institute for Basic Science nanotech
ETH Zurich Nano
Zurich, Switzerland
World-class technical university with FIRST lab and nano research
Twist Bioscience
South San Francisco, United States
Silicon-based DNA synthesis platform for synthetic biology
Nanopore Technologies
Oxford, United Kingdom
Nanopore-based DNA/RNA sequencing with portable devices
Element Biosciences
San Diego, United States
Benchtop DNA sequencing with accuracy at scale
Ultima Genomics
Newark, United States
Ultra-low-cost genome sequencing technology
LogicBio Therapeutics
Lexington, United States
Gene insertion technology using AAV and GeneRide platform
Sangamo Therapeutics
Brisbane, United States
Zinc finger nuclease gene editing and gene regulation
Mammoth Biosciences
Brisbane, United States
CRISPR diagnostics and therapeutics using novel Cas proteins
Sherlock Biosciences
Cambridge, United States
CRISPR-based molecular diagnostics platform
Precision BioSciences
Durham, United States
ARCUS genome editing for cell therapy and gene correction
Evonetix
Cambridge, United Kingdom
DNA synthesis company using semiconductor technology for desktop DNA writing
Molecular Assemblies
San Diego, United States
Enzymatic DNA synthesis company enabling rapid gene synthesis and DNA data storage
Catalog Technologies
Boston, United States
DNA data storage company developing massive-scale digital data storage in DNA
LogicBio Therapeutics
Lexington, United States
Genome editing company developing gene insertion medicines for pediatric diseases
Veracyte
South San Francisco, United States
Genomic diagnostics company improving cancer diagnosis and treatment
Pairwise
Durham, United States
Gene editing company developing better fruits and vegetables using CRISPR
Inari Agriculture
Cambridge, United States
Seed design company using gene editing for sustainable crop improvement
Noom
New York, United States
Behavior change platform for weight loss and health
edX
Cambridge, United States
Online learning platform founded by Harvard and MIT
MasterClass
San Francisco, United States
Streaming platform for classes taught by renowned experts and celebrities
Turnitin
Oakland, United States
Academic integrity and writing feedback platform
Vice Media
Brooklyn, United States
Youth media company with digital, TV, and film content
Trace Genomics
San Francisco, United States
Soil microbiome testing and analytics
Biome Makers
West Sacramento, United States
Soil and plant microbiome intelligence
Outschool
San Francisco, United States
Live online classes marketplace
JustAnswer
San Francisco, United States
JustAnswer is an online platform connecting users with verified experts across multiple fields including legal, medical, veterinary, technical support, and automotive, providing on-demand answers and consultations for everyday questions and problems. Founded in 2003 in San Francisco with over $100 million in funding and 500+ employees, JustAnswer has facilitated millions of expert consultations, serving users in over 196 countries. The platform employs thousands of credentialed professionals including lawyers, doctors, veterinarians, mechanics, and technicians who provide personalized answers to user questions through a pay-per-question or subscription model. JustAnswer's legal category connects users with licensed attorneys who can provide guidance on family law, contracts, estate planning, employment disputes, and other legal matters at a fraction of traditional consultation costs. The medical experts offer health advice, symptom assessment, and second opinions, though they appropriately direct users to emergency services for urgent situations. Veterinary professionals help pet owners with animal health concerns, behavior issues, and treatment options. The platform's technical support experts assist with computer problems, software issues, and consumer electronics troubleshooting. JustAnswer's question-and-answer format allows users to describe their situation in detail, upload photos or documents, and engage in back-and-forth conversation until their question is fully answered. The platform verifies expert credentials, tracks customer satisfaction ratings, and maintains quality standards through monitoring and feedback systems. Users can browse previously answered questions, benefiting from the knowledge base built by millions of interactions. With 24/7 availability, multilingual support, and expertise across dozens of specialties, JustAnswer provides accessible, affordable expert guidance for everyday problems that might otherwise require expensive professional consultations.
Nanosphere Inc
Northbrook, United States
Gold nanoparticle-based molecular diagnostics
DNA Nanobots
Cambridge, United States
DNA-based nanodevices for targeted therapeutics delivery, vaccines, and diagnostics
Bionano Genomics
San Diego, United States
Genome analysis tools using nanochannel technology
Cerahelix
Orono, United States
DNA-templated ceramic nanofiltration membranes