Lab-on-a-Chip
Microfluidic devices integrating nanoscale components
Nanosphere (Luminex)
Northbrook, United States
Developer of molecular diagnostics platform using gold nanoparticle probe technology for rapid disease detection
Exosome Diagnostics
Waltham, United States
Exosome Diagnostics, founded in 2008 in Waltham, Massachusetts, emerged as a global leader in exosome-based liquid biopsy technology before being acquired by Bio-Techne Corporation. The company pioneered the use of exosomes—nanoscale extracellular vesicles (30-150 nm) naturally released by cells—as biomarkers for non-invasive disease detection and monitoring. Exosomes contain genetic material, proteins, and other molecular cargo that reflect the state of their cell of origin, making them valuable diagnostic tools for cancer and other diseases. Exosome Diagnostics developed sophisticated isolation and analysis technologies to capture these nanovesicles from bodily fluids and extract clinically relevant biomarkers, particularly RNA and DNA molecules. The company's flagship product, the ExoDx Prostate Test (IntelliScore), represents a breakthrough in prostate cancer detection, analyzing exosomal RNA from urine samples to help determine the need for prostate biopsy, thereby reducing unnecessary invasive procedures. This non-invasive approach leverages the natural biology of exosomes, which are shed into circulation and easily accessible through liquid biopsies. Exosome Diagnostics also developed comprehensive exosome isolation kits enabling researchers and clinicians to harness these nanosized vesicles for biomarker discovery and diagnostic applications. The company raised over $100 million in funding and established strategic partnerships with pharmaceutical companies and research institutions. The acquisition by Bio-Techne expanded the reach of exosome diagnostics technology within a larger life sciences organization. Exosome-based diagnostics represent a paradigm shift from traditional tissue biopsies to liquid biopsies, offering less invasive, repeatable testing that can track disease progression and treatment response. As precision medicine advances, exosome diagnostics continues to play a crucial role in enabling earlier disease detection, personalized treatment selection, and real-time monitoring, establishing exosomes as a transformative platform in nano-diagnostics and molecular medicine.
10x Genomics
Pleasanton, United States
10x Genomics, founded in 2012 in Pleasanton, California, has revolutionized biological research through innovative microfluidic and nanoscale technologies that enable unprecedented resolution in genomics analysis. The company went public on NASDAQ under ticker TXG, reflecting its status as a major player in the genomics technology sector with over 1,000 employees worldwide. 10x Genomics specializes in single-cell analysis and spatial biology, utilizing sophisticated nanofluidic systems that manipulate individual cells and molecules within nanoliter-scale droplets and nanofabricated chambers. The company's flagship Chromium platform employs microfluidic partitioning to isolate individual cells into nanoliter-sized gel beads in emulsion (GEMs), where each cell receives a unique molecular barcode. This nanotechnology-enabled approach allows researchers to analyze gene expression, immune repertoires, and epigenetic states at single-cell resolution, revealing cellular heterogeneity previously obscured in bulk tissue analysis. The Visium spatial genomics platform combines tissue imaging with transcriptomics, using nanoscale capture arrays to map gene expression while preserving spatial context within tissue sections. The newer Xenium in situ platform pushes resolution further, enabling subcellular visualization of hundreds of genes simultaneously through multiplexed in situ hybridization with nanoscale precision. These technologies rely on advanced nanofabrication techniques, precise microfluidic control, and molecular barcoding strategies that operate at nanometer scales. 10x Genomics products have become essential tools in cancer research, immunology, neuroscience, and developmental biology, enabling discoveries about cellular diversity, disease mechanisms, and therapeutic targets. The company's success demonstrates how nanotechnology enables transformative advances in life sciences, making previously impossible measurements routine. With continued innovation in nanofluidics, molecular barcoding, and imaging technologies, 10x Genomics continues to expand the frontiers of biological understanding at the single-cell and subcellular levels.
Nanomix
Emeryville, United States
Nanomix, established in 2000 in Emeryville, California, is a pioneering company in nanosensor technology, specializing in carbon nanotube-based electronic biosensors for point-of-care medical diagnostics. The company has raised over $75 million in funding to develop its innovative diagnostic platform that leverages the exceptional electronic and chemical properties of carbon nanotubes for rapid, accurate medical testing. Carbon nanotubes, cylindrical nanostructures with diameters of just a few nanometers, exhibit extraordinary sensitivity to surface chemical changes, making them ideal transducers for biosensing applications. Nanomix's proprietary technology functionalizes carbon nanotubes with specific recognition molecules that bind target biomarkers, causing measurable changes in the nanotubes' electrical conductivity. This direct electronic detection mechanism enables rapid, label-free measurement of clinically relevant analytes. The company's flagship eLab diagnostic system brings laboratory-quality testing to the point of care, providing rapid results for critical biomarkers directly at the patient's bedside, in emergency departments, or in physician offices. The system can measure multiple analytes including blood gases, electrolytes, and metabolites from small blood samples, with results available in minutes rather than the hours typically required for central laboratory testing. This speed enables faster clinical decision-making, particularly critical in acute care settings. The nanosensor technology offers significant advantages including small sample volumes, minimal reagent consumption, and the potential for highly multiplexed testing. Nanomix's platform addresses the growing demand for decentralized diagnostic testing, aligning with trends toward personalized medicine and value-based healthcare. The company's work exemplifies how nanotechnology can transform medical diagnostics, bringing sophisticated analytical capabilities out of centralized laboratories and directly to patients. As point-of-care testing continues to expand globally, Nanomix's carbon nanotube-based sensors represent a significant technological advancement in making rapid, accurate diagnostic information immediately available to healthcare providers.
Nanobix
Basel, Switzerland
Nanobix, founded in 2018 in Basel, Switzerland, is an innovative biotechnology company developing next-generation nanopore-based biosensors for rapid point-of-care diagnostics. Based in Basel, a global hub for pharmaceutical and biotechnology innovation, Nanobix leverages cutting-edge nanotechnology to create diagnostic devices that can detect disease biomarkers quickly and accurately outside traditional laboratory settings. The company's nanopore biosensor platform utilizes nanoscale pores—typically 1-10 nanometers in diameter—embedded in thin membranes as highly sensitive molecular detectors. When target molecules pass through or interact with these nanopores under an applied electrical field, they produce characteristic changes in ionic current that serve as molecular fingerprints for identification and quantification. This single-molecule detection approach offers exceptional sensitivity and specificity, enabling detection of biomarkers at clinically relevant concentrations from small sample volumes. Nanobix's technology addresses critical needs in point-of-care diagnostics, where rapid results can significantly impact patient management and treatment decisions. The nanopore platform is particularly well-suited for detecting nucleic acids, proteins, and other biomolecules associated with infectious diseases, cancer, and cardiovascular conditions. Unlike conventional diagnostic methods requiring extensive sample preparation and laboratory infrastructure, nanopore sensors can potentially deliver results in minutes from raw or minimally processed samples. The company has secured over $5 million in funding to advance its platform through development and validation stages. Switzerland's strong scientific ecosystem, with world-class universities and research institutions, provides Nanobix with access to expertise in nanofabrication, biosensor development, and clinical diagnostics. The company's work represents an important advancement in translating nanopore technology, originally developed for DNA sequencing, into broader diagnostic applications. As healthcare systems increasingly emphasize decentralized testing and rapid diagnosis, Nanobix's nanopore biosensors could play a significant role in bringing laboratory-quality diagnostics to point-of-care settings worldwide.
Oxford Nanopore Technologies
Oxford, United Kingdom
Pioneer in nanopore DNA/RNA sequencing technology enabling real-time, long-read sequencing
Pacific Biosciences
Menlo Park, United States
Developer of single molecule real-time (SMRT) DNA sequencing technology
Illumina
San Diego, United States
Global leader in DNA sequencing using nanoscale flow cell technology
NanoString Technologies
Seattle, United States
Developer of molecular barcoding technology for gene expression analysis
Nano-Bio-MEMS
Cincinnati, United States
Developer of MEMS-based nanobiosensors
NanoTemper Technologies
Munich, Germany
Developer of microscale thermophoresis for biomolecular analysis
Pacific Biosciences
Menlo Park, United States
Developer of SMRT sequencing using zero-mode waveguides
Singular Genomics
La Jolla, United States
Next-gen sequencing platform with nanoscale engineering
Nabsys
Providence, United States
Developer of electronic genome mapping using nanochannels
Quantum Biosystems
Tokyo, Japan
Single-molecule electrical sequencing technology
Nutcracker Therapeutics
Emeryville, United States
Automated mRNA manufacturing with microfluidic systems
NanoScent
Haifa, Israel
AI-powered nano-sensor platform for scent detection
NanoEnTek
Seoul, South Korea
Lab-on-a-chip and cell analysis systems
Brooks Automation
Chelmsford, United States
Automation and cryogenic solutions for semiconductors
T2 Biosystems
Lexington, United States
Magnetic nanoparticle-based diagnostics
Quantum-Si
Branford, United States
Single-molecule protein sequencing
Ginkgo Bioworks
Boston, United States
Cell programming platform for bio-based products and materials
DNA Script
Paris, France
Enzymatic DNA synthesis for on-demand oligo production
Standard BioTools
South San Francisco, United States
Microfluidics and mass cytometry for life science research
Nuclera
Cambridge, United Kingdom
Desktop protein synthesis and bioprinting technology
Sphere Fluidics
Cambridge, United Kingdom
Picodroplet microfluidics for single-cell analysis and antibody discovery
Dolomite Microfluidics
Royston, United Kingdom
Microfluidic systems for droplet generation and particle synthesis
Fluigent
Paris, France
Pressure-based microfluidic flow control systems for research
Micronit
Enschede, Netherlands
Glass and silicon microfluidic chips manufacturing for life sciences
Attomol
Bronkow, Germany
Nanoparticle-based diagnostic systems
Exiqon
Vedbaek, Denmark
Locked nucleic acid technology for RNA research and diagnostics
Abbott Laboratories
Abbott Park, United States
Healthcare company with nanotechnology-based diagnostics and glucose monitoring
Dexcom
San Diego, United States
Continuous glucose monitoring using advanced nanosensor technology
Quotient Sciences
Nottingham, United Kingdom
Drug development services including nanoparticle formulation technologies
STEMCELL Technologies
Vancouver, Canada
Cell separation and culture products using magnetic nanoparticle technology
Akadeum Life Sciences
Ann Arbor, United States
Microbubble technology for fast, gentle cell separation and enrichment
Beckman Coulter Diagnostics
Brea, United States
Clinical diagnostics with nanoparticle-based immunoassays and flow cytometry
Siemens Healthineers
Erlangen, Germany
Medical diagnostics with nanotechnology-based immunoassays and imaging agents
Roche Diagnostics
Basel, Switzerland
Clinical diagnostics leader with nanoparticle-enhanced immunoassays
Bio-Techne
Minneapolis, United States
Life science tools including nanoparticle-based reagents and spatial biology
PerkinElmer
Waltham, United States
Analytical instruments and diagnostics with nanoparticle-based assay technologies
Cepheid
Sunnyvale, United States
Molecular diagnostics with microfluidic cartridges and nanoscale detection
bioMérieux
Marcy-l'Étoile, France
In vitro diagnostics with nanoparticle-based detection technologies
Hologic
Marlborough, United States
Molecular diagnostics with advanced detection technologies for women's health
Exact Sciences
Madison, United States
Cancer screening using molecular diagnostic and nanoparticle detection technologies
Guardant Health
Redwood City, United States
Liquid biopsy for cancer detection using circulating tumor DNA analysis
GRAIL
Menlo Park, United States
Multi-cancer early detection using cell-free DNA and advanced sequencing
Natera
Austin, United States
Cell-free DNA testing for prenatal screening and cancer detection
Invitae
San Francisco, United States
Genetic testing company with comprehensive hereditary cancer panels
Myriad Genetics
Salt Lake City, United States
Molecular diagnostics for hereditary cancer and prenatal screening
Color Health
Burlingame, United States
Population-scale genetic testing and COVID-19 testing infrastructure
23andMe
Sunnyvale, United States
Consumer genetics company with health and ancestry DNA testing
BGI Genomics
Shenzhen, China
Genomics company with sequencing platforms and diagnostic services
Berry Genomics
Beijing, China
Non-invasive prenatal testing and genetic diagnostics in China
Annoroad Gene Technology
Beijing, China
Genomic sequencing services and bioinformatics solutions
Burning Rock Biotech
Guangzhou, China
Cancer genomics and liquid biopsy diagnostics company in China
Singlera Genomics
Shanghai, China
DNA methylation-based early cancer detection and liquid biopsy
MGI Tech
Shenzhen, China
DNA sequencing instruments and reagents using proprietary technology
Merck Millipore
Darmstadt, Germany
Lab filtration and bioprocessing with nanopore membrane technology
Sartorius
Göttingen, Germany
Bioprocess and lab equipment with nanofiltration and membrane technology
NanoEnTek
Seoul, South Korea
Microfluidics and nano-scale diagnostic devices for life sciences
Nautilus Biotechnology
Seattle, United States
Single-molecule proteomics platform for comprehensive protein analysis
Nanopore Technologies
Oxford, United Kingdom
Nanopore-based DNA/RNA sequencing with portable devices
Element Biosciences
San Diego, United States
Benchtop DNA sequencing with accuracy at scale
Ultima Genomics
Newark, United States
Ultra-low-cost genome sequencing technology
NanoCellect Biomedical
San Diego, United States
Microfluidic cell sorting for single-cell applications
Refeyn
Oxford, United Kingdom
Mass photometry for label-free protein characterization
Nanotemper Technologies
Munich, Germany
Protein stability and binding measurement instruments
Dolomite Microfluidics
Royston, United Kingdom
Microfluidic systems for droplet generation and particle synthesis
RainDance Technologies (Bio-Rad)
Billerica, United States
Droplet digital PCR technology, acquired by Bio-Rad
Sophion Bioscience
Copenhagen, Denmark
Automated patch clamp systems for ion channel research
Nanion Technologies
Munich, Germany
Automated patch clamp and ion channel research tools
Mammoth Biosciences
Brisbane, United States
CRISPR diagnostics and therapeutics using novel Cas proteins
Sherlock Biosciences
Cambridge, United States
CRISPR-based molecular diagnostics platform
BICO Group (Cellink)
Gothenburg, Sweden
Life science technology with bioprinting and bioinks for tissue engineering and drug discovery
Aspect Biosystems
Vancouver, Canada
Microfluidic bioprinting for tissue therapeutics and drug delivery applications
Prellis Biologics
San Francisco, United States
Holographic bioprinting for vascularized tissues and organs at high speed and resolution
Intuitive Surgical
Sunnyvale, United States
Pioneer in robotic-assisted minimally invasive surgery with da Vinci systems
Medtronic Surgical Robotics
Dublin, Ireland
Global medical device leader with Hugo robotic-assisted surgery platform
Berkeley Lights
Emeryville, United States
Digital cell biology company using optoelectronic positioning for single cell manipulation
Molecular Assemblies
San Diego, United States
Enzymatic DNA synthesis company enabling rapid gene synthesis and DNA data storage
Abbott Laboratories
Abbott Park, United States
Global healthcare company with diagnostics and medical device solutions
Becton Dickinson
Franklin Lakes, United States
Global medical technology company advancing the world of health
Insulet Corporation
Acton, United States
Medical device company developing tubeless insulin pump technology
Tandem Diabetes Care
San Diego, United States
Medical device company developing advanced insulin pump technology
GE HealthCare
Chicago, United States
Medical technology company providing imaging, monitoring, and diagnostics solutions
Philips Healthcare
Amsterdam, Netherlands
Health technology company focused on improving health through innovation
Baxter International
Deerfield, United States
Healthcare company focused on products for hospitalized patients
Olympus Medical
Tokyo, Japan
Precision technology company with leading endoscopy and surgical solutions
Resmed
San Diego, United States
Medical device company developing products for sleep apnea and respiratory care
Fisher & Paykel Healthcare
Auckland, New Zealand
Medical device company developing respiratory care and acute care products
Masimo
Irvine, United States
Medical technology company developing noninvasive patient monitoring solutions
iRhythm Technologies
San Francisco, United States
Digital healthcare company providing ambulatory cardiac monitoring services
Qiagen
Hilden, Germany
Provider of sample to insight solutions for molecular diagnostics
Veracyte
South San Francisco, United States
Genomic diagnostics company improving cancer diagnosis and treatment
CareDx
Brisbane, United States
Precision medicine company focused on transplant diagnostics
Adaptive Biotechnologies
Seattle, United States
Biotechnology company developing immune-driven medicine through sequencing
ICU Medical
San Clemente, United States
Medical device company developing infusion therapy and critical care products
Haemonetics
Boston, United States
Global healthcare company providing blood management solutions
Merit Medical
South Jordan, United States
Medical device company manufacturing products for interventional procedures
Natus Medical
Middleton, United States
Medical device company developing neurodiagnostic and newborn care solutions
Butterfly Network
Burlington, United States
Medical device company developing handheld whole-body ultrasound
Vicarious Surgical
Waltham, United States
Robotics company developing next-gen surgical robots with human-like movement
Procept BioRobotics
Redwood City, United States
Surgical robotics company developing Aquablation therapy for BPH
Asensus Surgical
Durham, United States
Medical device company developing digitized laparoscopic surgical systems
CMR Surgical
Cambridge, United Kingdom
Surgical robotics company developing the Versius surgical system
Distalmotion
Lausanne, Switzerland
Medical robotics company developing the Dexter robotic surgical system
Oscar Health
New York, United States
Technology-focused health insurance company with member-centric approach
Noom
New York, United States
Behavior change platform for weight loss and health
Prospera Technologies
Tel Aviv, Israel
AI and computer vision for agriculture
Arable
Princeton, United States
Agricultural sensing and analytics platform
Clover Health
Franklin, United States
Medicare Advantage insurer using AI to improve health outcomes
Bright Health
Minneapolis, United States
Health insurance company partnering with care delivery systems
Devoted Health
Waltham, United States
Medicare Advantage plans with technology-driven care model
Alan
Paris, France
Digital health insurance company in Europe
Labster
Copenhagen, Denmark
Virtual science lab simulations for higher education
Nearpod
Fort Lauderdale, United States
Interactive lesson platform for K-12 student engagement
Renaissance Learning
Bloomington, United States
K-12 assessment and learning analytics platform
Alan
Paris, France
Digital health insurance in Europe
BetterUp
San Francisco, United States
Coaching and mental fitness platform
Alan
Paris, France
European health insurance
BIMA
Stockholm, Sweden
Mobile insurance for emerging markets
Nava PBC
Washington, United States
Public benefit corporation for government technology
Connecterra
Amsterdam, Netherlands
AI for dairy farming
JustAnswer
San Francisco, United States
JustAnswer is an online platform connecting users with verified experts across multiple fields including legal, medical, veterinary, technical support, and automotive, providing on-demand answers and consultations for everyday questions and problems. Founded in 2003 in San Francisco with over $100 million in funding and 500+ employees, JustAnswer has facilitated millions of expert consultations, serving users in over 196 countries. The platform employs thousands of credentialed professionals including lawyers, doctors, veterinarians, mechanics, and technicians who provide personalized answers to user questions through a pay-per-question or subscription model. JustAnswer's legal category connects users with licensed attorneys who can provide guidance on family law, contracts, estate planning, employment disputes, and other legal matters at a fraction of traditional consultation costs. The medical experts offer health advice, symptom assessment, and second opinions, though they appropriately direct users to emergency services for urgent situations. Veterinary professionals help pet owners with animal health concerns, behavior issues, and treatment options. The platform's technical support experts assist with computer problems, software issues, and consumer electronics troubleshooting. JustAnswer's question-and-answer format allows users to describe their situation in detail, upload photos or documents, and engage in back-and-forth conversation until their question is fully answered. The platform verifies expert credentials, tracks customer satisfaction ratings, and maintains quality standards through monitoring and feedback systems. Users can browse previously answered questions, benefiting from the knowledge base built by millions of interactions. With 24/7 availability, multilingual support, and expertise across dozens of specialties, JustAnswer provides accessible, affordable expert guidance for everyday problems that might otherwise require expensive professional consultations.
Calibrate
New York, United States
Metabolic health company
Nanion Technologies
Munich, Germany
Automated patch clamp and ion channel research
Spectradyne
Signal Hill, United States
Nanoparticle Analyzer based on microfluidic resistive pulse sensing
Ademtech
Pessac, France
Superparamagnetic beads for diagnostics
Elveflow
Paris, France
Microfluidic instruments for nanoparticle synthesis
NanoString Technologies
Seattle, United States
Molecular barcode technology for gene expression analysis
Nanion Technologies
Munich, Germany
Automated patch clamp systems for ion channel research
Nanomix
Emeryville, United States
Carbon nanotube-based electronic biosensors
Mepsgen
Seoul, South Korea
NanoCalibur automated nanoparticle production using microfluidic technology
Cellino
Cambridge, United States
AI-guided laser platform for personalized cell therapy manufacturing
Nanomedical Diagnostics
San Diego, United States
Graphene-based diagnostic platforms for accurate, timely health information
Nostics
Amsterdam, Netherlands
AI-powered nanotechnology diagnostics for fast and accurate disease detection
Diagnostic anSERS
College Park, United States
Handheld SERS-based detector for drugs and explosives identification