mRNA Delivery

Nanocarriers for messenger RNA therapeutics and vaccines

75 companies 13 countries
A

Arrowhead Research

Pasadena, United States

Biopharmaceutical company developing targeted RNAi therapeutics using proprietary TRiM platform

NASDAQ: ARWR
M

Moderna

Cambridge, United States

Pioneer in mRNA therapeutics using lipid nanoparticle (LNP) delivery technology for vaccines and medicines

NASDAQ: MRNA
B

BioNTech

Mainz, Germany

Immunotherapy company leveraging lipid nanoparticle delivery for mRNA vaccines and cancer therapies

NASDAQ: BNTX
A

Acuitas Therapeutics

Vancouver, Canada

Leading developer of lipid nanoparticle (LNP) delivery systems for nucleic acid therapeutics, partner for COVID-19 vaccines

P

Precision NanoSystems

Vancouver, Canada

Provider of instruments for scalable nanoparticle manufacturing for gene therapies and mRNA vaccines

A

Alnylam Pharmaceuticals

Cambridge, United States

Pioneer in RNAi therapeutics using lipid nanoparticle delivery for treatment of genetic diseases

NASDAQ: ALNY
I

Intellia Therapeutics

Cambridge, United States

Gene editing company using lipid nanoparticle delivery for in vivo CRISPR therapeutics

NASDAQ: NTLA
N

NanoVation Therapeutics

Vancouver, Canada

Developer of next-generation lipid nanoparticle delivery systems for RNA therapeutics

V

Verve Therapeutics

Boston, United States

Gene editing company using lipid nanoparticle delivery for cardiovascular disease treatment

NASDAQ: VERV
S

Sirnaomics

Gaithersburg, United States

Clinical-stage biopharmaceutical company developing RNAi therapeutics using polypeptide nanoparticle delivery

NASDAQ: SIRN
C

CureVac

Tubingen, Germany

Pioneer in mRNA technology using lipid nanoparticle delivery for vaccines and therapeutics

NASDAQ: CVAC
G

Genevant Sciences

Cambridge, United States

Developer of lipid nanoparticle and ligand conjugate delivery systems for genetic medicines

A

Arcturus Therapeutics

San Diego, United States

Developer of LUNAR lipid nanoparticle delivery platform for mRNA medicines

NASDAQ: ARCT
S

Silence Therapeutics

London, United Kingdom

Pioneer in precision RNAi medicines using mRNAi GOLD platform with GalNAc delivery

NASDAQ: SLN
D

Dicerna Pharmaceuticals

Lexington, United States

Developer of GalXC RNAi platform for targeted gene silencing therapeutics

A

Arrowhead Pharmaceuticals

Pasadena, United States

Leader in RNAi therapeutics using targeted delivery

NASDAQ: ARWR public
T

Translate Bio

Lexington, United States

mRNA therapeutics company with proprietary LNP technology, acquired by Sanofi

E

Etherna Immunotherapies

Niel, Belgium

mRNA immunotherapy company with proprietary LNP delivery technology

e

eTheRNA Immunotherapies

Niel, Belgium

mRNA immunotherapy with proprietary delivery platform

S

Strand Therapeutics

Boston, United States

Programmable mRNA therapeutics with logic gates

N

Nutcracker Therapeutics

Emeryville, United States

Automated mRNA manufacturing with microfluidic systems

M

Mina Therapeutics

London, United Kingdom

Small activating RNA therapeutics with LNP delivery

T

Tidal Therapeutics

Cambridge, United States

LNP-based in vivo gene therapy for immune cells, acquired by Sanofi

R

ReNAgade Therapeutics

Cambridge, United States

RNA delivery technology for extrahepatic targets

N

NanoTherapeutics

Alachua, United States

Biopharmaceutical nanotechnology development

L

LNP Japan

Tokyo, Japan

Lipid nanoparticle manufacturing services for RNA therapeutics

N

Nanobio2Pharma

Bordeaux, France

Nanoparticle drug formulation and CDMO services

E

Ethris GmbH

Planegg, Germany

SNIM RNA stabilized mRNA therapeutics

E

Entos Pharmaceuticals

Edmonton, Canada

Fusogenix nucleic acid delivery platform

A

Arrowhead Pharmaceuticals

Pasadena, United States

TRiM RNAi therapeutics platform

NASDAQ: ARWR public
N

Nitto Denko Avecia

Milford, United States

Oligonucleotide and nucleic acid CDMO services

S

Sixfold Bioscience

London, United Kingdom

AI-driven nanoparticle delivery optimization

L

Lonza

Basel, Switzerland

Life sciences and specialty ingredients

SIX: LONN public
C

CR Micro

Wuxi, China

Power semiconductor foundry

SSE STAR: 688396 public
A

Alnylam Pharmaceuticals

Cambridge, United States

Leader in RNAi therapeutics using lipid nanoparticle delivery for genetic diseases

NASDAQ: ALNY public
A

Arbutus Biopharma

Vancouver, Canada

Develops lipid nanoparticle technology for hepatitis B and other infectious diseases

NASDAQ: ABUS public
A

Arcturus Therapeutics

San Diego, United States

RNA medicines company using LUNAR lipid nanoparticle delivery platform

NASDAQ: ARCT public
A

Acuitas Therapeutics

Vancouver, Canada

Develops lipid nanoparticle delivery systems for nucleic acid therapeutics

G

Genevant Sciences

Cambridge, United States

Lipid nanoparticle and ligand conjugate delivery platforms for genetic medicines

V

Verve Therapeutics

Cambridge, United States

Gene editing company for cardiovascular disease using base editing and LNP delivery

NASDAQ: VERV public
A

Arrowhead Pharmaceuticals

Pasadena, United States

RNAi therapeutics company developing targeted delivery systems for genetic medicines

NASDAQ: ARWR public
D

Dicerna Pharmaceuticals

Lexington, United States

RNAi therapeutics using GalXC delivery platform for liver-targeted gene silencing

A

Afrigen Biologics

Cape Town, South Africa

African mRNA vaccine hub developing lipid nanoparticle delivery technology

C

Catalent

Somerset, United States

Contract manufacturer with lipid nanoparticle and advanced drug delivery capabilities

NYSE: CTLT public
L

Lonza Pharma

Basel, Switzerland

Life sciences company with lipid nanoparticle manufacturing for mRNA therapeutics

SIX: LONN public
E

Evonik Health Care

Essen, Germany

Specialty chemicals for pharmaceutical drug delivery including lipid nanoparticles

XETRA: EVK public
C

Croda Health Care

Snaith, United Kingdom

Specialty ingredients including lipids for nanoparticle drug delivery

LSE: CRDA public
P

Piramal Pharma Solutions

Mumbai, India

CDMO with capabilities in lipid nanoparticle and advanced drug delivery systems

NSE: PPLPHARMA public
S

Siegfried Holding

Zofingen, Switzerland

Pharmaceutical CDMO with particle engineering and formulation capabilities

SIX: SFZN public
C

Corden Pharma

Basel, Switzerland

CDMO specializing in lipids and lipid nanoparticle manufacturing

E

Exelead

Indianapolis, United States

CDMO focused on liposomes and lipid nanoparticle drug delivery systems

T

T&T Scientific

Knoxville, United States

Liposome and lipid nanoparticle preparation equipment and services

N

Northern Lipids

Vancouver, Canada

CDMO for liposomal and lipid nanoparticle drug delivery formulations

A

Avanti Polar Lipids

Alabaster, United States

High-purity lipids and liposomes for research and drug delivery applications

N

NOF Corporation

Tokyo, Japan

PEG-lipid conjugates and functional lipids for liposome drug delivery

TSE: 4403 public
M

Merck Life Science

Darmstadt, Germany

Life science products including lipids and nanomaterials for drug delivery research

XETRA: MRK public
E

Evonik Health Care

Essen, Germany

Drug delivery polymers and lipid nanoparticle components

XETRA: EVK public
A

Alnylam Pharmaceuticals

Cambridge, United States

Pioneer in RNAi therapeutics with lipid nanoparticle delivery

NASDAQ: ALNY public
S

Stoke Therapeutics

Bedford, United States

Antisense oligonucleotides to upregulate protein expression

NASDAQ: STOK public
D

Dicerna Pharmaceuticals

Lexington, United States

RNAi therapeutics using GalNAc delivery (acquired by Novo Nordisk)

C

Croda International

Snaith, United Kingdom

Specialty chemicals with Avanti lipids for LNP formulations

LSE: CRDA public
E

Entos Pharmaceuticals

Edmonton, Canada

Fusogenix DNA delivery platform for gene therapy

K

Kernal Biologics

Cambridge, United States

Self-amplifying mRNA with immune-silent delivery

R

Replicate Bioscience

San Diego, United States

Self-replicating RNA therapeutics platform

L

Laronde

Cambridge, United States

Endless RNA (eRNA) technology for persistent protein expression

O

Orna Therapeutics

Cambridge, United States

Circular RNA platform for cell therapy and protein replacement

L

Lonza Cell and Gene

Basel, Switzerland

Global CDMO providing cell and gene therapy manufacturing services

SIX: LONN public
S

SeraGene Therapeutics

London, United Kingdom

RNA and nanomedicine treatments for blood disorders

A

Aurora Biosynthetics

Singapore, Singapore

GMP manufacturing of plasmid DNA, mRNA and lipid nanoparticles for Asia Pacific

M

Mepsgen

Seoul, South Korea

NanoCalibur automated nanoparticle production using microfluidic technology

E

Exsilio Therapeutics

Boston, United States

mRNA platform for revocable genetic medicines

C

Cello Therapeutics

San Diego, United States

Cell membrane-coated nanoparticles for immunotherapy delivery with FDA IND status

E

ExonanoRNA

Boston, United States

RNA nanoparticles and exosomes for cancer therapeutics

P

Phosphorex

Hopkinton, United States

CDMO for lipid nanoparticle and liposome drug delivery

D

DIANT Pharma

San Diego, United States

LiFT continuous manufacturing system for lipid nanoparticles at GMP scale