Theranostics

Combined diagnostic and therapeutic nanoplatforms

21 companies 10 countries
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Nanobiotix

Paris, France

Clinical-stage biotechnology company pioneering nanomedicine with first-in-class radioenhancers for cancer treatment

Euronext: NANO
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Nanospectra Biosciences

Houston, United States

Developer of gold nanoshell-based thermal ablation therapy for cancer treatment

N

Nanocure

Tel Aviv, Israel

Nanocure, established in 2015 in Tel Aviv, Israel, is an innovative nanomedicine company focused on developing next-generation cancer therapies through advanced nanoparticle-based drug delivery systems. The company's proprietary platform leverages the unique properties of engineered nanoparticles to achieve precise targeting of cancer cells while minimizing damage to healthy tissue, addressing one of the most significant challenges in oncology treatment. Nanocure's targeted nanoparticle therapeutics are designed to overcome the limitations of conventional chemotherapy, which often causes severe side effects due to non-selective distribution throughout the body. The company's nanoparticle formulations utilize sophisticated surface modifications, including targeting ligands and stealth coatings, to enhance circulation time, improve tumor accumulation through the enhanced permeability and retention effect, and facilitate active targeting to specific cancer cell markers. This multifaceted approach enables higher drug concentrations at tumor sites while reducing systemic exposure and associated toxicities. The technology platform is versatile, capable of encapsulating various therapeutic agents including small molecule drugs, peptides, and nucleic acids, making it applicable to multiple cancer types and treatment modalities. Nanocure's nanoparticles are engineered at the nanoscale (typically 10-200 nanometers) to optimize biological interactions, cellular uptake, and intracellular drug release. The company has secured over $15 million in funding to advance its pipeline through preclinical and clinical development stages. Israel's strong biotechnology ecosystem and expertise in nanomedicine provide Nanocure with access to world-class research facilities, clinical networks, and regulatory support. As cancer treatment increasingly moves toward personalized medicine and targeted therapies, Nanocure's nanoparticle platform represents a significant advancement in delivering more effective and safer cancer treatments, positioning the company as an important player in the rapidly evolving field of cancer nanotherapy.

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Nanobiotix SA

Cambridge, United States

Clinical-stage nanomedicine company developing first-in-class radioenhancers using hafnium oxide nanoparticles

NASDAQ: NBTX
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Nanosphere Biosciences

Boulder, United States

Developer of nanobubble-based therapeutic delivery systems

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NanoMedTrix

Berlin, Germany

Nanoparticle-based immunotherapy platform

E

Exicure

Chicago, United States

Spherical nucleic acid therapeutics platform

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Nano Therapeutics

Mumbai, India

Nano-based drug delivery systems for cancer therapy

N

Nanospectra Biosciences

Houston, United States

Gold nanoshell photothermal ablation therapy for cancer

N

NH TherAguix

Villeurbanne, France

Gadolinium-based nanoparticles for MRI-guided radiotherapy

T

Taiwan Liposome Company

Taipei, Taiwan

BioSeizer and NanoX liposomal drug delivery platforms

TWSE: 4152 public
C

Celsion Corporation

Lawrenceville, United States

ThermoDox heat-activated liposomal doxorubicin

NASDAQ: CLSN public
O

Oncobiologics

Cranbury, United States

Biosimilar development with advanced formulation technology

S

Siemens Healthineers

Erlangen, Germany

Medical diagnostics with nanotechnology-based immunoassays and imaging agents

XETRA: SHL public
S

Seagen

Bothell, United States

ADC pioneer (Adcetris, Padcev) acquired by Pfizer

V

Varian Medical Systems

Palo Alto, United States

Medical device company focused on radiation oncology treatments

E

Elekta

Stockholm, Sweden

Medical technology company developing precision radiation medicine

OMX: EKTA-B public
n

nanoTherics

Newcastle upon Tyne, United Kingdom

Magnetic nanoparticle research tools

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Nano4Tarmed

Coimbra, Portugal

Nanotechnology platforms for targeted medicine and cancer treatment

S

Sona Nanotech

Halifax, Canada

Non-toxic gold nanorods for photothermal therapy and tumor-targeting drug delivery

M

MagForce

Berlin, Germany

Magnetic nanoparticle hyperthermia therapy for brain tumors