Nanofluidics
Fluid behavior and devices at the nanoscale
Porifera
Hayward, United States
Developer of forward osmosis membranes using carbon nanotube and graphene oxide
NanoMedical Systems
Austin, United States
Developer of nanochannel drug delivery implants for sustained therapeutic release
Precision NanoSystems
Vancouver, Canada
Provider of instruments for scalable nanoparticle manufacturing for gene therapies and mRNA vaccines
10x Genomics
Pleasanton, United States
10x Genomics, founded in 2012 in Pleasanton, California, has revolutionized biological research through innovative microfluidic and nanoscale technologies that enable unprecedented resolution in genomics analysis. The company went public on NASDAQ under ticker TXG, reflecting its status as a major player in the genomics technology sector with over 1,000 employees worldwide. 10x Genomics specializes in single-cell analysis and spatial biology, utilizing sophisticated nanofluidic systems that manipulate individual cells and molecules within nanoliter-scale droplets and nanofabricated chambers. The company's flagship Chromium platform employs microfluidic partitioning to isolate individual cells into nanoliter-sized gel beads in emulsion (GEMs), where each cell receives a unique molecular barcode. This nanotechnology-enabled approach allows researchers to analyze gene expression, immune repertoires, and epigenetic states at single-cell resolution, revealing cellular heterogeneity previously obscured in bulk tissue analysis. The Visium spatial genomics platform combines tissue imaging with transcriptomics, using nanoscale capture arrays to map gene expression while preserving spatial context within tissue sections. The newer Xenium in situ platform pushes resolution further, enabling subcellular visualization of hundreds of genes simultaneously through multiplexed in situ hybridization with nanoscale precision. These technologies rely on advanced nanofabrication techniques, precise microfluidic control, and molecular barcoding strategies that operate at nanometer scales. 10x Genomics products have become essential tools in cancer research, immunology, neuroscience, and developmental biology, enabling discoveries about cellular diversity, disease mechanisms, and therapeutic targets. The company's success demonstrates how nanotechnology enables transformative advances in life sciences, making previously impossible measurements routine. With continued innovation in nanofluidics, molecular barcoding, and imaging technologies, 10x Genomics continues to expand the frontiers of biological understanding at the single-cell and subcellular levels.
Nanobix
Basel, Switzerland
Nanobix, founded in 2018 in Basel, Switzerland, is an innovative biotechnology company developing next-generation nanopore-based biosensors for rapid point-of-care diagnostics. Based in Basel, a global hub for pharmaceutical and biotechnology innovation, Nanobix leverages cutting-edge nanotechnology to create diagnostic devices that can detect disease biomarkers quickly and accurately outside traditional laboratory settings. The company's nanopore biosensor platform utilizes nanoscale pores—typically 1-10 nanometers in diameter—embedded in thin membranes as highly sensitive molecular detectors. When target molecules pass through or interact with these nanopores under an applied electrical field, they produce characteristic changes in ionic current that serve as molecular fingerprints for identification and quantification. This single-molecule detection approach offers exceptional sensitivity and specificity, enabling detection of biomarkers at clinically relevant concentrations from small sample volumes. Nanobix's technology addresses critical needs in point-of-care diagnostics, where rapid results can significantly impact patient management and treatment decisions. The nanopore platform is particularly well-suited for detecting nucleic acids, proteins, and other biomolecules associated with infectious diseases, cancer, and cardiovascular conditions. Unlike conventional diagnostic methods requiring extensive sample preparation and laboratory infrastructure, nanopore sensors can potentially deliver results in minutes from raw or minimally processed samples. The company has secured over $5 million in funding to advance its platform through development and validation stages. Switzerland's strong scientific ecosystem, with world-class universities and research institutions, provides Nanobix with access to expertise in nanofabrication, biosensor development, and clinical diagnostics. The company's work represents an important advancement in translating nanopore technology, originally developed for DNA sequencing, into broader diagnostic applications. As healthcare systems increasingly emphasize decentralized testing and rapid diagnosis, Nanobix's nanopore biosensors could play a significant role in bringing laboratory-quality diagnostics to point-of-care settings worldwide.
Oxford Nanopore Technologies
Oxford, United Kingdom
Pioneer in nanopore DNA/RNA sequencing technology enabling real-time, long-read sequencing
Pacific Biosciences
Menlo Park, United States
Developer of single molecule real-time (SMRT) DNA sequencing technology
Illumina
San Diego, United States
Global leader in DNA sequencing using nanoscale flow cell technology
Boston Micro Fabrication
Maynard, United States
Developer of micro-precision 3D printing systems
Silex Microsystems
Jarfalla, Sweden
Pure-play MEMS foundry for advanced microsystems
Nabsys
Providence, United States
Developer of electronic genome mapping using nanochannels
Nutcracker Therapeutics
Emeryville, United States
Automated mRNA manufacturing with microfluidic systems
NanoEnTek
Seoul, South Korea
Lab-on-a-chip and cell analysis systems
CNRS LAAS
Toulouse, France
French national MEMS and nano research center
Standard BioTools
South San Francisco, United States
Microfluidics and mass cytometry for life science research
Nuclera
Cambridge, United Kingdom
Desktop protein synthesis and bioprinting technology
Sphere Fluidics
Cambridge, United Kingdom
Picodroplet microfluidics for single-cell analysis and antibody discovery
Dolomite Microfluidics
Royston, United Kingdom
Microfluidic systems for droplet generation and particle synthesis
Fluigent
Paris, France
Pressure-based microfluidic flow control systems for research
Micronit
Enschede, Netherlands
Glass and silicon microfluidic chips manufacturing for life sciences
Cepheid
Sunnyvale, United States
Molecular diagnostics with microfluidic cartridges and nanoscale detection
Merck Millipore
Darmstadt, Germany
Lab filtration and bioprocessing with nanopore membrane technology
NanoEnTek
Seoul, South Korea
Microfluidics and nano-scale diagnostic devices for life sciences
NanoCellect Biomedical
San Diego, United States
Microfluidic cell sorting for single-cell applications
Dolomite Microfluidics
Royston, United Kingdom
Microfluidic systems for droplet generation and particle synthesis
RainDance Technologies (Bio-Rad)
Billerica, United States
Droplet digital PCR technology, acquired by Bio-Rad
MEMSCAP
Grenoble, France
Custom MEMS solutions and foundry services
MEMSPRO (CSEM)
Neuchâtel, Switzerland
MEMS R&D and technology transfer center
Aspect Biosystems
Vancouver, Canada
Microfluidic bioprinting for tissue therapeutics and drug delivery applications
Iron Ox
Gilroy, United States
Fully autonomous robot farms growing produce using AI and robotics
Koniku
San Jose, United States
Wetware company merging synthetic biology with silicon for neuromorphic computing
Starfish Space
Kent, United States
Spacecraft servicing company developing autonomous docking technology
Phase Four
Hawthorne, United States
Plasma propulsion company for small satellites
Berkeley Lights
Emeryville, United States
Digital cell biology company using optoelectronic positioning for single cell manipulation
Insulet Corporation
Acton, United States
Medical device company developing tubeless insulin pump technology
CareDx
Brisbane, United States
Precision medicine company focused on transplant diagnostics
Skillz
San Francisco, United States
Mobile esports platform for competitive gaming tournaments
Buffalo Automation
Buffalo, United States
AI-powered autonomous marine vessels
PortXchange
Rotterdam, Netherlands
Port call optimization and collaboration
Meituan
Beijing, China
Food delivery and local services
Grab
Singapore, Singapore
Grab is Southeast Asia's leading superapp platform offering ride-hailing, food delivery, digital payments, and financial services across eight countries including Singapore, Indonesia, Malaysia, Thailand, Vietnam, Philippines, Myanmar, and Cambodia. Founded in 2012 in Singapore (originally as MyTeksi in Malaysia) and publicly traded on NASDAQ under ticker GRAB, the company employs over 10,000 people and serves millions of users daily. Grab's ride-hailing service dominates most Southeast Asian markets, offering motorcycles, cars, and taxi services tailored to local preferences and infrastructure. GrabFood has become the region's largest food delivery platform, partnering with hundreds of thousands of restaurants and merchants. GrabMart provides on-demand delivery of groceries and essentials from supermarkets, convenience stores, and specialty retailers. GrabExpress offers same-day parcel delivery for businesses and consumers. GrabPay, the company's digital wallet, enables cashless payments across Grab services and at millions of merchant locations, becoming a significant player in Southeast Asia's digital payments ecosystem. GrabFinancial extends into lending, insurance, and investment products designed for the region's largely underbanked population. The platform's success stems from deep localization, understanding diverse market needs from motorcycle taxis in dense cities to car services in suburban areas. Grab's driver and merchant partners number in the millions, providing critical earning opportunities across the region. The superapp strategy creates network effects where users access multiple services through one platform, increasing engagement and lifetime value. With Southeast Asia's young, mobile-first population and rapidly growing middle class, Grab is positioned as essential digital infrastructure for the region's economic development and digital transformation.
Swiftly
San Francisco, United States
Transit data platform
Moovit
Ness Ziona, Israel
Mobility as a Service platform
Nanion Technologies
Munich, Germany
Automated patch clamp and ion channel research
Micralyne
Edmonton, Canada
MEMS and microfluidics foundry services
Elveflow
Paris, France
Microfluidic instruments for nanoparticle synthesis
TeraPore Technologies
South San Francisco, United States
Block copolymer-based nanofiltration membranes
Envue Technologies
Stockholm, Sweden
Nanofluidic scattering microscopy for protein and biomolecule characterization
Nexalus
Dublin, Ireland
Impinging liquid jet CPU cooling technology
Coolit Systems
Calgary, Canada
Direct liquid cooling solutions for data centers